
Other creams like papaverine and verapamil are used in special cases like Peyronie’s disease. These creams work locally with fewer side effects, but it is best to use them after talking to a doctor. If you’re looking for a quick, effective, and easy-to-use treatment for ED, topical creams offer a promising option. These creams work by applying medication directly to the penis to increase blood flow and help achieve an erection, often with fewer side effects than oral pills. In this article, we will explore the different types of ED creams available, including popular options like alprostadil creams and the new Food and Drug Administration-approved MED3000 gel.
National Institute of Diabetes and Digestive and Kidney Diseases (NIDDK). Randomized study of testosterone gel as adjunctive therapy to sildenafil in hypogonadal men with erectile dysfunction who do not respond to sildenafil alone. U.S. Food and Drug Administration (FDA). Scoping review exploring advancements in topical agent therapies for erectile dysfunction.
A double-blind placebo-controlled evaluation of the effect of topical sildenafil on erectile dysfunction. Alpostadil in cream — a new option of treating erectile dysfunctions in diabetes. Hims & Hers has strict sourcing guidelines to ensure our content is accurate and current. We rely on peer-reviewed studies, academic research institutions, and medical associations. We strive to use primary sources and refrain from using tertiary references.
Dr. Kelly Brown is a board certified Urologist and fellowship trained in Andrology. She is an accomplished men’s health expert with a robust background in healthcare innovation, clinical medicine, and academic research. Dr. Brown was previously Medical Director of a male fertility startup where she lead strategy and design of their digital health platform, an innovative education and telehealth model for delivering expert male fertility care. We will also discuss who should use these creams, who should avoid them, their effectiveness, side effects, and how to choose the right one for you. Erectile dysfunction creams are a form of medication applied directly to the skin of the penis. These creams are designed to increase blood flow and induce an erection. You may wonder: how do these creams for erectile dysfunction actually work — and how do they compare to topical sprays like those discussed in delay sprays and ED?
| Brand Name | Main Active Ingredient | Price Range | User Ratings | Availability |
|---|---|---|---|---|
| ErecCream Plus | L-arginine | $20-$40 | 4.5/5 | Online, pharmacies |
| VigorGel | Yohimbine | $15-$35 | 4.2/5 | Online only |
| LibidoBoost | Maca Extract | $10-$25 | 4.0/5 | Stores, online |
| VitalErect | Ginseng Extract | $25-$50 | 4.3/5 | Pharmacies |
| PassionGel | DHEA | $30-$60 | 4.1/5 | Special order |
Oral ED pills such as sildenafil or tadalafil work systemically, meaning they deliver medication into the blood vessels for distribution throughout the body.
| Product | Dosage | Quantity + Bonus | Price | |
|---|---|---|---|---|
| Kamagra | 100mg | 60 + 4 Pills | 201.34€ 191.75€ | |
| Viagra Original | 100mg | 4 Pills | 40.94€ 38.99€ | |
| Cialis Generic | 60mg | 180 + 10 Pills | 313.11€ 298.20€ | |
| Cialis Black | 80mg | 360 + 20 Pills | 639.78€ 609.31€ | |
| Kamagra Soft Tabs | 100 mg | 84 + 4 Pills | 233.05€ 221.95€ | |
| Viagra Soft Tabs | 100mg | 30 + 4 Pills | 83.06€ 79.10€ | |
| Levitra Original | 20mg | 64 + 4 Pills | 298.45€ 284.24€ | |
| Kamagra 100 mg | 100 mg | 120 + 6 Pills | 330.74€ 314.99€ | |
| Viagra Generic | 200mg | 180 + 10 Pills | 277.56€ 264.34€ | |
| Levitra Original | 20mg | 48 + 4 Pills | 235.14€ 223.94€ | |
| Cialis Original | 20mg | 22 + 2 Pills | 129.20€ 123.05€ | |
| Viagra Original | 100mg | 48 + 4 Pills | 207.15€ 197.29€ |
These topical creams, on the other hand, act locally. They are applied to the surface of the penis and help minimize systemic side effects.
She completed her undergraduate studies at University of North Carolina at Chapel Hill (go Heels!) with a Bachelor of Science in Radiologic Science and a Minor in Chemistry. She took a position at University of California Los Angeles as a radiologic technologist in the department of Interventional Cardiology, further solidifying her passion for medicine. She also pursued the unique opportunity to lead departmental design and operational development at the Ronald Reagan UCLA Medical Center, sparking her passion for the business of healthcare. Dr. Brown then went on to obtain her doctorate in medicine from the prestigious Northwestern University - Feinberg School of Medicine and Masters in Business Administration from Northwestern University - Kellogg School of Management, with a concentration in Healthcare Management.
During her surgical residency in Urology at University of California San Francisco, she utilized her research year to focus on innovations in telemedicine and then served as chief resident with significant contributions to clinical quality improvement. Dr. Brown then completed her Andrology Fellowship at Medical College of Wisconsin, furthering her expertise in male fertility, microsurgery, and sexual function. Her dedication to caring for patients with compassion, understanding, as well as a unique ability to make guys instantly comfortable discussing anything from sex to sperm makes her a renowned clinician. In addition, her passion for innovation in healthcare combined with her business acumen makes her a formidable leader in the field of men’s health.
Dr. Brown is an avid adventurer; summiting Mount Kilimanjaro in Tanzania (twice!) and hiking the incredible Torres del Paine Trek in Patagonia, Chile. She deeply appreciates new challenges and diverse cultures on her travels. She lives in Denver with her husband, two children, and beloved Bernese Mountain Dog. You can find Dr. Each of them has different active ingredients and mechanisms of action. Some of the commonly known creams include Alprostadil, the recently Food and Drug Administration-approved MED3000 (Eroxon) gel, and other options such as Papaverine and Verapamil creams. Additionally, brands like Veda and Pamel offer herbal or combined ingredient creams targeting ED symptoms.
Though many men don’t like to talk about it, ejaculation problems are very common. Some of the most common issues include premature, delayed, or retrograde ejaculation. Your pelvic floor is a lot like plumbing in your home: you never really think about it unless something goes wrong. When you think of male sexual dysfunction, concerns like erectile dysfunction (ED) or premature ejaculation (PE) probably come to mind first. But there’s another sex-related issue that’s more common in men than you might expect: difficulty orgasming.
Dr Sandip completed his training in Psychiatry and sexual medicine in the UK. A post-graduate in Psychiatry from KMC Manipal, he worked in the UK for over 8 years following a one-year research post at NIMHANS, Bangalore. With an interest in the fields of sexual health and functioning, he has authored articles in books and peer-reviewed journals. A recipient of the student of the year award by BSART in 2010, he is currently a consultant psychiatrist and sexual and relationship therapist with a belief in a holistic and psychotherapeutic approach to treating psychological distress. Dr.
Anvi Dogra is a medical writer and healthcare professional with a doctoral background in clinical sciences. She leverages her medical training to produce deeply researched, people first content across the wellness industries. With a "360-degree" understanding of the healthcare industry, Dr. Anvi focuses on bridge-building between clinical data and patient wellness. Known for her ability to make complex medical topics accessible and engaging, Dr. Each cream is different in terms of effectiveness, application method, availability, and suitability for different users. In the following sections, we will explore these topical treatments in more detail, discussing how they work, who should consider using them, and their safety profiles. Alprostadil is the primary active agent in most topical ED creams.
| Medication Type | Possible Interaction | Risk Level | Recommendations |
|---|---|---|---|
| Nitrate medications (for heart) | Increased risk of severe hypotension | High | Do not use without doctor consultation |
| Blood pressure medications | Potential blood pressure changes | Moderate | Consult healthcare provider |
| Other hormonal therapies | Altered hormone balance | Moderate | Medical supervision required |
| Antidepressants | Possible worsening of side effects or reduced efficacy | Low to moderate | Talk to doctor before use |
It is a synthetic analog of prostaglandin E1 (PGE1) that helps to relax smooth muscle in the penile tissue and arteries.
Brown on LinkedIn for more information. Urology Residency, University of California San Francisco Urology Residency, University of California San Francisco Northwestern University Feinberg School of MedicineB.S. in Radiologic Science, Chemistry Minor, University of North Carolina at Chapel Hill Northwestern University Feinberg School of MedicineB.S. in Radiologic Science, Chemistry Minor, University of North Carolina at Chapel Hill Cowan, B, Walker, K., Rodgers, K., Agyemang, J. Hormonal Management Improves Semen Analysis Parameters in Men with Abnormal cenforce tablets Concentration, Motility, and/or Morphology.
Fertility and Sterility, Volume 118, Issue 5, e4. Cowan, B, Walker, K., Rodgers, K., Agyemang, J. Regret Regarding Fertility Preservation Decisions Among Male Cancer Patients. The Journal of Urology, 201(Supplement 4), e680-e681. Feasibility Study of Video Telehealth Clinic Visits in Urology.
The Journal of Urology, 201(Supplement 4), e545-e545. Erectile dysfunction is a condition in which you have trouble getting or keeping an erection firm enough for satisfying sex. Erectile dysfunction affects as many as 30 million men in the United States. Premature ejaculation (PE) is a sexual dysfunction characterized by a short ejaculatory latency, a perceived lack of control about the timing of ejaculation, and distress and interpersonal difficulty related to ejaculating too quickly. Low testosterone or testosterone deficiency, also known as hypogonadism, is a condition in which patients develop symptoms such as low sex drive, erectile dysfunction (ED), and fatigue because the body doesn’t produce enough testosterone. This increases blood flow in the penis to induce an erection [1].
Studies and clinical trials have shown that alprostadil cream can increase erectile function scores and produce erections within 10 to 12 minutes.
These erections are effective and can last for over an hour [1].
The application process involves applying it to the glans penis using a small amount of cream.
Alprostadil creams such as Vitaros and Stardill are used primarily for men who cannot take oral PDE-5 inhibitors.
Anvi ensures that all health information is grounded in clinical evidence. Our experts continually monitor the health and wellness space, and we update our articles when new information becomes available. If you're wondering what is the best cream for erectile dysfunction, three main options are available. Alprostadil creams like Vitaros and Stardill help increase blood vardenafil oral flow and are good for men who cannot take oral pills. MED3000 is an over-the-counter gel that works in about 10 minutes and does not need a prescription. In India, prescription-based alprostadil topical creams are generally expensive due to limited availability and regulatory controls. Based on publicly available listings and clinical observations, their price typically ranges from around ₹2,000 to ₹5,000 or more per treatment pack, though actual costs may vary depending on pharmacy, location, and prescription requirements.