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• Understanding the mechanism: PDE5 enzyme inhibition.
• During sexual arousal, nitric oxide is released in penile tissue.
• This triggers production of cGMP, a chemical that relaxes arteries.
• PDE5 breaks down cGMP, ending the erection.
• Tadalafil inhibits PDE5, allowing cGMP to accumulate.
• This sustains the relaxed state of arteries and blood flow.
• The effect is localized; it does not cause arousal by itself.
• This scientific basis is shared by all PDE5 inhibitor medications.

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• Tell your doctor about any other medications being taken beforehand.
• Overdose symptoms include dizziness, chest pain, or vision changes.
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